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--- teaching:cndm:cndm_neuroimaging_instructions_lit_rev [2019/10/16 10:27] – created anthony
+++ teaching:cndm:cndm_neuroimaging_instructions_lit_rev [2019/10/16 10:35] (current) – anthony
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+==== - What other cognitive skills are associated with this region? ====
+After you have picked the most important brain region (Instructions document item II.C.3.a), figure out how to identify that region and look it up on Neurosynth's "Locations" page (click the "Locations" link at the top of the main page.)
+You do this in one of two ways:
+  - If you came across a set of 3D coordinates (x,y,z) in any of your reading or Neurosynth browsing, you can type them in the "Data for coordinates" fields.
+  - Find a picture showing where your region is in the brain, and then click on the 3 views of the brain on the Neurosynth Locations page until you think the green crosshairs are at your location. Then click the "What's here?" button.
+The web page will reload, showing a brain map with crosshairs and bright colors centered on the coordinates that you entered/clicked on.
+[{{:teaching:neurosynth_locations_maps.png}}]
+\\
+----
+**We will not use the "Functional connectivity and coactivation maps" that appear**, but here is a brief explanation about them for those who might be interested. This color map represents something different from the meta-analysis activation maps that you produced earlier. This time, the color map indicates the probability that the location at these coordinates is "connected" with other locations in the brain. I put "connected" in quotes because the color map is not based on measures of **anatomical** connectivity, even thought those exist (e.g. diffusion tensor imaging maps of white matter pathways). Neurosynths' "Functional connectivity and coactivation maps" display something like the probability that other regions will be active in a functional MRI, given that the region under the crosshairs is active.
+**We will** click on the "Association" link that appears above the brain map. The resulting web page gives a table listing the names of other Neurosynth meta-analysis maps (that already exist, somewhere on the Neurosynth web server) that have especially high values at the coordinates we entered.
+[{{:teaching:neurosynth_associations.png| Click the "Associations" link to see this list of terms associated with your coordinates.}}]
+\\
+----
+We can use the names of these meta-analyses as a set of rough guesses about what other cognitive skills might be associated with this brain location. Again, the activation maps from Neurosynth meta-analyses are interesting because they represent pretty good answers to questions like, "If all I know about a neuroimaging study is that the term X appeared in the article, which brain regions were likely to be active?" Right now we are considering something like the reverse question: "If all I know about a neuroimaging study is that coordinate X,Y,Z was active, what terms were likely to appear in the article?" It requires an additional leap of faith to guess that just because an article included the term "language comprehension" (for example), that our brain region is actively involved in producing that cognitive skill, but it's a great start.
+== Copy the table from the "Associations" page and paste it at the bottom of your answer. ==
+Again, this table should have only 10 rows.
+Paste the table into the proper location in the summary document template.
+\\
+----
+\\